Naturally Inspired
01-04-12
Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Professor of Bioinspired Engineering, and colleagues are studying the properties of the zebrafish embryonic heart to address problems as diverse as ringing in the ears and overheated electronics. They have also developed the first pump built entirely from biological building blocks. “We can actually be more clever than nature,” Gharib says. “We can get inspired by nature and use engineering to come up with better functions. Just look at 747s—they fly from LAX to La Guardia much more efficiently than any bird could.”
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GALCIT
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health
Morteza Gharib
Bioinspired
Stimulating Electrode Array Assists Paraplegic Man to Stand and Move Legs Voluntarily
05-20-11
Joel W. Burdick, Professor of Mechanical Engineering and Bioengineering, and colleagues including Yu-Chong Tai, Professor of Electrical Engineering and Mechanical Engineering, have used a stimulating electrode array to assist a paralyzed man to stand, step on a treadmill with assistance, and, over time, to regain voluntary movements of his limbs. Using a combination of experimentation, computational models of the array and spinal cord, and machine-learning algorithms, Professor Burdick and his colleagues are now trying to optimize the stimulation pattern to achieve the best effects, and to improve the design of the electrode array. Further advances in the technology should lead to better control of the stepping and standing processes.
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EE
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Yu-Chong Tai
MCE
Joel Burdick
Professor Gharib Named Vice Provost
07-29-10
Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Professor of Bio-Inspired Engineering, is the new Vice Provost with a special focus on research. Professor Gharib has made contributions to a wide array of research topics ranging from the fundamental analysis of biological flows, to the development of bio-inspired medical devices, to advanced flow visualization techniques. One of his more unusual studies was his work with a SURF student several years ago where they raised a 30000-pound obelisk into place using a single kite and speculated that the ancient Egyptians may have moved the massive stones from which the pyramids were built and raised obelisks by flying them into place! His breadth, technical strength, and enthusiasm will serve him and Caltech well as he takes on the role of Vice Provost. [Caltech Today Article]
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Morteza Gharib
Ali Hajimiri Awarded $6 Million to Develop Self-Healing Circuits
04-08-09
Over the past few decades, the transistors in computer chips have become progressively smaller and faster, allowing upwards of a billion individual transistors to be packed into a single circuit, thus shrinking the size of electronic devices. But these circuits have an intractable design flaw: if just a single transistor fails, the entire circuit also fails. One novel way around the problem is a so-called self-healing circuit. Such circuits are "inspired by biological systems that constantly heal themselves in the presence of random and intentional failures," says Caltech professor Ali Hajimiri.
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Ali Hajimiri
Morteza Gharib and Abbas Nasiraei Moghaddam Show Function of Helical Band in Heart
12-01-08
Using an MRI technique, Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Professor of Bioengineering, and his colleague Abbas Nasiraei Moghaddam, a Caltech graduate and visitor in Bioengineering, were able to create some of the first dynamic images of normal heart muscle in action at the tissue level. They showed that a muscular band--which wraps around the inner chambers of the heart in a helix--is actually a sort of twisting highway along which each contraction of the heart travels. "We tagged and traced small tissue elements in the heart, and looked at them in space, so we could see how they moved when the heart contracts," Gharib explains. "In this way, we were able to see where the maximum physical contraction occurs in the heart and when--and to show that it follows this intriguing helical loop."
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Morteza Gharib
Changhuei Yang Develops "Microscope on a Chip"
07-28-08
Changhuei Yang, Assistant Professor of Electrical Engineering and Bioengineering, and colleagues have turned science fiction into reality with their development of a super-compact high-resolution microscope, small enough to fit on a finger tip. This "microscopic microscope" operates without lenses but has the magnifyingpower of a top-quality optical microscope, can be used in the field to analyze blood samples for malaria or check water supplies for giardia and other pathogens, and can be mass-produced for around $10.
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Changhuei Yang
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