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Conversations on Artificial Intelligence: The Future of Personalized Medicine

03-20-23

As part of Conversations on Artificial Intelligence, a webinar series hosted by the Caltech Science Exchange, Andrew and Peggy Cherng Professor of Electrical Engineering and Medical Engineering Azita Emami discusses how her lab incorporates artificial intelligence (AI) into medical devices to improve health and enhance quality of life. Watch the conversation. [Caltech story]

Tags: EE research highlights MedE Azita Emami

Knots Smaller Than Human Hair Make Materials Unusually Tough

03-09-23

In the latest advance in nano- and micro-architected materials, engineers at Caltech have developed a new material made from numerous interconnected microscale knots. The knots make the material far tougher than identically structured but unknotted materials: they absorb more energy and are able to deform more while still being able to return to their original shape undamaged. [Caltech story]

Tags: APhMS research highlights MedE Julia Greer Sammy Shaker Weiting Deng Widianto Moestopo

Wavefront Shaping: From Telescopes to Biological Tissue

02-24-23

Researchers, led by Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, have made a major step forward in medical imaging by taking inspiration from the field of astronomy. In astronomy, the light that reaches telescopes is distorted by the earth's atmosphere, resulting in blurry images of planets, satellites, and other cosmic objects. The earth's atmosphere is what's known as a scattering medium; it scatters light, making images appear unfocused and cloudy. Wavefront shaping is a method of generating focused light by reversing the optical distortion caused by the atmosphere. In this method, a reflective device, like a mirror, "shapes" light waves to counterbalance distortion. It's similar to a person wearing active noise-cancelling headphones to combat ambient noise. [Caltech story]

Tags: EE research highlights MedE Lihong Wang

A GPS for Smart Pills

02-13-23

Caltech researchers have developed proxies for human doctors that are small enough to travel through the human body and help diagnose ailments. These "smart pills" are typically swallowed, and as they pass through the digestive tract, they collect health data, record images, and even deliver drugs. [Caltech story]

Tags: EE research highlights MedE Azita Emami Mikhail Shapiro Saransh Sharma

Seeing More with a Needle-Shaped Laser

12-02-22

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering, and his research team show how they developed a new variant of photoacoustic microscopy (PAM) called needle-shaped beam photoacoustic microscopy (NB-PAM). NB-PAM has a depth of field nearly 14 times greater than what was achievable before. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Rui Cao

New Process Allows 3-D Printing of Microscale Metallic Parts

12-01-22

Engineers at Caltech have developed a method for 3-D printing pure and multicomponent metals, at a resolution that is, in some cases, an order of magnitude smaller than previously possible. "We had to develop a new way of doing it, and we couldn't rely on heat to build our structures," says Max Saccone. [Caltech story]

Tags: APhMS research highlights MedE MCE MCE Julia Greer Max Saccone Rebecca Gallivan Daryl Yee Kai Narita

Emerging Metal 3D Printing Technology from Caltech: Hydrogel Infusion

10-28-22

Caltech has been doing interesting work in 3D printing for a number of years now, especially Professor Julia Greer and the Greer Group. The team works in hierarchical, nano, battery and other new materials, as well as processes for 3D printing. One novel area that the team have been doing exploring over the years is related to hydrogel derived materials. [Read full story]

Tags: APhMS research highlights MedE Julia Greer

Beaming Clean Energy From Space

10-26-22

Once considered science fiction, technology capable of collecting solar power in space and beaming it to Earth to provide a global supply of clean and affordable energy is moving closer to reality. Through the Space-based Solar Power Project (SSPP), a team of Caltech researchers is working to deploy a constellation of modular spacecraft that collect sunlight, transform it into electricity, then wirelessly transmit that electricity wherever it is needed—including to places that currently have no access to reliable power. "This is an extraordinary and unprecedented project," says Harry Atwater, Otis Booth Leadership Chair, Division of Engineering and Applied Science; Howard Hughes Professor of Applied Physics and Materials Science; Director, Liquid Sunlight Alliance. "It exemplifies the boldness and ambition needed to address one of the most significant challenges of our time, providing clean and affordable energy to the world." [Caltech story]

Tags: APhMS EE research highlights MedE MCE Harry Atwater Ali Hajimiri Sergio Pellegrino

High-speed Camera Captures Signals Traveling Through Nerve Cells

10-07-22

Scientists have developed a new ultrafast camera that can record footage of impulses as they travel through nerve cells. The camera technology, known as differentially enhanced compressed ultrafast photography (Diff-CUP), was developed in the lab of Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering. "Seeing nerve signals is fundamental to our scientific understanding but has not yet been achieved owing to the lack of speed and sensitivity provided by existing imaging methods," Wang says. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Yide Zhang Binglin Shen Tong Wu Jerry Zhao Joseph Jing Peng Wang Kanomi Sasaki-Capela William Dunphy David Garrett Konstantin Maslov Weiwei Wang

Laser Light Offers New Tool for Treating Bone Cancer

09-20-22

Of the many ways to treat cancer, the oldest, and maybe most tried and true, is surgery. The goal is to remove all of the cancerous tissue while preserving as much of the surrounding healthy material as possible. "It's very hard to grow bone, so if you cut out bone, you basically lose it," says Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering. A new diagnostic imaging technology developed by researchers at Caltech is offering surgeons the ability to make cuts 10 times more precisely, allowing them to preserve as much as 1,000 times more healthy tissue and to give patients easier recoveries. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Rui Cao Samuel Davis Yilin Luo Yide Zhang