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Tiny Shape-Shifting Polymers Developed for Potential Medical Applications

01-04-21

Julia Greer, Ruben F. and Donna Mettler Professor of Materials Science, Mechanics and Medical Engineering; Fletcher Jones Foundation Director of the Kavli Nanoscience Institute, has developed a process for generating three-dimensional architected polymers with heat-dependent "shape memory" properties: that is, when heated, the material folds and unfolds itself into a new preordained shape. These shape memory polymers could one day be used to perform complex tasks inside the human body, such as unclogging a blocked artery or pulling out a blood clot. [Caltech story]

Tags: APhMS research highlights MedE Julia Greer KNI Luizetta Elliott

Lihong Wang Named to National Academy of Inventors

12-10-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Wang lab has developed photoacoustic imaging that allows researchers to see into biological tissues noninvasively, and to peer deeper into the body by nearly two orders of magnitude compared to conventional optical microscopy. [Caltech story] [List of 2020 Fellows]

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Changhuei Yang Named to National Academy of Inventors

12-10-20

Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Yang lab develops technologies aimed at transforming the conventional microscope so that it can be used for high-throughput, automated applications. He also works on the use of "time-reversal" techniques to undo the effect of tissue light scattering. [Caltech story] [List of 2020 Fellows]

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Lihong Wang Receives NIH BRAIN Grant

12-07-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has received funding for neuroscience projects from the National Institutes of Health's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Wang and his team aim to develop a technology called 3D photoacoustic computed tomography (PACT) that will rapidly image large-scale neural activity in human brains with high sensitivity. "Photoacoustic imaging of adult human brains is one of the most challenging frontiers in our field," says Wang. "It requires innovation to overcome the signal attenuation and wavefront distortion due to the skull. I'm glad that the NIH has the vision to fund this worthy research direction." [Caltech story]

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Isabella Yang Named to Forbes Magazine's 30 Under 30

12-01-20

Graduate student Yiran (Isabella) Yang has been named to Forbes magazine's 30 Under 30 for developing wearable sweat sensors to help intervene earlier and monitor progression of heart disease and other health problems. She recently adapted the sensors to detect Covid-19 antibodies in human saliva. The list honors people from 12 fields that range from finance and science to music and entertainment. [Forbes 30 Under 30 Full List]

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Ultrafast Camera Films 3-D Movies at 100 Billion Frames Per Second

10-19-20

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed technology that can reach blistering speeds of 70 trillion frames per second, fast enough to see light travel. Just like the camera in your cell phone, though, it can only produce flat images. Now, Wang's lab has gone a step further to create a camera that not only records video at incredibly fast speeds but does so in three dimensions. [Caltech story]

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New Device Powers Wearable Sensors Through Human Motion

10-16-20

Wei Gao, Assistant Professor of Medical Engineering, has been developing sensors as well as novel approaches to power them. Previously, he created a sensor that could monitor health indicators in human sweat that is powered by sweat itself. Now, Gao has developed a new way to power wireless wearable sensors: He harvests kinetic energy that is produced by a person as they move around. "Instead of using fancy materials, we use commercially available flexible circuit boards," he says. "This material is cheap and very durable and mechanically robust over long periods of time." [Caltech story]

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Professor Gao Unveils Sensor that Rapidly Detects COVID-19 Infection Status, Severity, and Immunity

10-02-20

One feature of the COVID-19 virus that makes it so difficult to contain is that it can be easily spread to others by a person who has yet to show any signs of infection. Wei Gao, Assistant Professor of Medical Engineering, has developed a new type of multiplexed test (a test that combines multiple kinds of data) with a low-cost sensor that may enable the at-home diagnosis of a COVID infection through rapid analysis of small volumes of saliva or blood, without the involvement of a medical professional, in less than 10 minutes. "This is the only telemedicine platform I've seen that can give information about the infection in three types of data with a single sensor," Gao says. "In as little as a few minutes, we can simultaneously check these levels, so we get a full picture about the infection, including early infection, immunity, and severity." [Caltech story]

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Research Selected for JFM Cover

09-22-20

The Journal of Fluid Mechanics has selected "Effect of the dynamic slip boundary condition on the near-wall turbulent boundary layer" by Cong Wang, Research Engineer, and Morteza Gharib, Hans W. Liepmann Professor of Aeronautics and Bioinspired Engineering; Booth-Kresa Leadership Chair, Center for Autonomous Systems and Technologies; Director, Graduate Aerospace Laboratories; Director, Center for Autonomous Systems and Technologies, as its cover article for volume 901, October 2020.

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Advancing Future Quantum Science Efforts

08-27-20

Five new Department of Energy centers will apply quantum information science to emerging technologies. The centers will develop cutting-edge quantum technologies for use in a wide range of possible applications including scientific computing; fundamental physics and chemistry research; and the design of solar cells and of new materials and pharmaceuticals. Caltech faculty will participate in four of the new science centers: the Quantum Systems Accelerator, led by the Lawrence Berkeley National Laboratory, also known as Berkeley Lab; the Quantum Science Center, led by Oak Ridge National Laboratory; Q-NEXT, led by Argonne National Laboratory; and the Co-design Center for Quantum Advantage, led by Brookhaven National Laboratory. [Caltech story]

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