Wavefront Shaping: From Telescopes to Biological Tissue
02-24-23
Researchers, led by Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, have made a major step forward in medical imaging by taking inspiration from the field of astronomy. In astronomy, the light that reaches telescopes is distorted by the earth's atmosphere, resulting in blurry images of planets, satellites, and other cosmic objects. The earth's atmosphere is what's known as a scattering medium; it scatters light, making images appear unfocused and cloudy. Wavefront shaping is a method of generating focused light by reversing the optical distortion caused by the atmosphere. In this method, a reflective device, like a mirror, "shapes" light waves to counterbalance distortion. It's similar to a person wearing active noise-cancelling headphones to combat ambient noise. [Caltech story]
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Lihong Wang
Seeing More with a Needle-Shaped Laser
12-02-22
Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering, and his research team show how they developed a new variant of photoacoustic microscopy (PAM) called needle-shaped beam photoacoustic microscopy (NB-PAM). NB-PAM has a depth of field nearly 14 times greater than what was achievable before. [Caltech story]
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Lihong Wang
Rui Cao
Beaming Clean Energy From Space
10-26-22
Once considered science fiction, technology capable of collecting solar power in space and beaming it to Earth to provide a global supply of clean and affordable energy is moving closer to reality. Through the Space-based Solar Power Project (SSPP), a team of Caltech researchers is working to deploy a constellation of modular spacecraft that collect sunlight, transform it into electricity, then wirelessly transmit that electricity wherever it is needed—including to places that currently have no access to reliable power. "This is an extraordinary and unprecedented project," says Harry Atwater, Otis Booth Leadership Chair, Division of Engineering and Applied Science; Howard Hughes Professor of Applied Physics and Materials Science; Director, Liquid Sunlight Alliance. "It exemplifies the boldness and ambition needed to address one of the most significant challenges of our time, providing clean and affordable energy to the world." [Caltech story]
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Harry Atwater
Ali Hajimiri
Sergio Pellegrino
Laser Light Offers New Tool for Treating Bone Cancer
09-20-22
Of the many ways to treat cancer, the oldest, and maybe most tried and true, is surgery. The goal is to remove all of the cancerous tissue while preserving as much of the surrounding healthy material as possible. "It's very hard to grow bone, so if you cut out bone, you basically lose it," says Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering. A new diagnostic imaging technology developed by researchers at Caltech is offering surgeons the ability to make cuts 10 times more precisely, allowing them to preserve as much as 1,000 times more healthy tissue and to give patients easier recoveries. [Caltech story]
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Lihong Wang
Rui Cao
Samuel Davis
Yilin Luo
Yide Zhang