Studying Chaos with One of the World's Fastest Cameras
01-14-21
There are things in life that can be predicted reasonably well. The tides rise and fall. A billiard ball bounces around a table according to orderly geometry. And then there are things that defy easy prediction: The hurricane that changes direction without warning. The splashing of water in a fountain. These phenomena and others like them can be described as chaotic systems. Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed a new tool that might help to better understand chaotic systems. [Caltech story]
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Lihong Wang Named to National Academy of Inventors
12-10-20
Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Wang lab has developed photoacoustic imaging that allows researchers to see into biological tissues noninvasively, and to peer deeper into the body by nearly two orders of magnitude compared to conventional optical microscopy. [Caltech story] [List of 2020 Fellows]
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Changhuei Yang Named to National Academy of Inventors
12-10-20
Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering, has been named fellow of the National Academy of Inventors (NAI). Election as a fellow is the highest professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society. The Yang lab develops technologies aimed at transforming the conventional microscope so that it can be used for high-throughput, automated applications. He also works on the use of "time-reversal" techniques to undo the effect of tissue light scattering. [Caltech story] [List of 2020 Fellows]
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Lihong Wang Receives NIH BRAIN Grant
12-07-20
Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has received funding for neuroscience projects from the National Institutes of Health's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Wang and his team aim to develop a technology called 3D photoacoustic computed tomography (PACT) that will rapidly image large-scale neural activity in human brains with high sensitivity. "Photoacoustic imaging of adult human brains is one of the most challenging frontiers in our field," says Wang. "It requires innovation to overcome the signal attenuation and wavefront distortion due to the skull. I'm glad that the NIH has the vision to fund this worthy research direction." [Caltech story]
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Seeing Through Opaque Media
05-12-20
Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering, has developed a technique that combines fluorescence and ultrasound to peer through opaque media, such as biological tissue. "We hope that one day this method can be deployed to extend the operating depth of fluorescence microscopy and help image fluorescent labeled cells deep inside living animals," says Yang. [Caltech story]
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New Ultrafast Camera Takes 70 Trillion Pictures Per Second
05-04-20
A new camera developed by Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, is capable of taking as many as 70 trillion frames per second. The camera technology, which Wang calls compressed ultrafast spectral photography (CUSP), combines a laser that emits extremely short pulses of laser light that last only one quadrillionth of a second (one femtosecond) with optics and a specialized type of camera. The technology could open up new avenues of research in fields that include fundamental physics, next-generation semiconductor miniaturization, and the life sciences. "We envision applications in a rich variety of extremely fast phenomena, such as ultrashort light propagation, wave propagation, nuclear fusion, photon transport in clouds and biological tissues, and fluorescent decay of biomolecules, among other things," Wang says. [Caltech story]
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Professor Wang Advances Photoacoustic Imaging Technology
02-25-20
Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed variants of photoacoustic imaging that can show organs moving in real time, develop three-dimensional (3-D) images of internal body parts, and even differentiate cancerous cells from healthy cells. Photoacoustic imaging, a technique for examining living materials through the use of laser light and ultrasonic sound waves, has many potential applications in medicine because of its ability to show everything from organs to blood vessels to tumors. Wang has now further advanced photoacoustic imaging technology with what he calls Photoacoustic Topography Through an Ergodic Relay (PATER), which aims to simplify the equipment required for imaging of this type. [Caltech story]
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Professor Wang Develops World's Fastest Camera
01-21-20
Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, has developed the world's fastest camera, a device capable of taking 10 trillion pictures per second. It's so fast that it can even capture light traveling in slow motion. "What we've done is to adapt standard phase-contrast microscopy so that it provides very fast imaging, which allows us to image ultrafast phenomena in transparent materials," says Wang. [Caltech story]
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Lihong Wang
