Sensors play a very important role in all aspect of modern life. This course is an essential introduction to a variety of physical, chemical and biological sensors that are used in medicine and healthcare. The fundamental recognition mechanisms, transduction principles and materials considerations for designing powerful sensing and biosensing devices will be covered. We will also discuss the development of emerging electronic-skin, wearable and soft electronics toward personalized health monitoring. Participants in the course will develop proposals for novel sensing technologies to address the current medical needs.