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Ultra-Thin Camera Creates Images Without Lenses

06-22-17

Professor Ali Hajimiri and colleagues have developed a new camera design that replaces the lenses with an ultra-thin optical phased array (OPA). The OPA does computationally what lenses do using large pieces of glass: it manipulates incoming light to capture an image. "Here, like most other things in life, timing is everything. With our new system, you can selectively look in a desired direction and at a very small part of the picture in front of you at any given time, by controlling the timing with femto-second—quadrillionth of a second—precision," says Professor Hajimiri. [Caltech story] [ENGenious silicon photonics feature]

Tags: EE research highlights MedE Ali Hajimiri

Cutting Down on Cancer Surgeries

05-17-17

Engineers at the Optical Imaging Laboratory led by Professor Lihong Wang have developed an imaging technology that could help surgeons removing breast cancer lumps confirm that they have cut out the entire tumor—reducing the need for additional surgeries. “What if we could get rid of the waiting? With 3D photoacoustic microscopy, we could analyze the tumor right in the operating room, and know immediately whether more tissue needs to be removed,” Professor Wang explains. [Caltech story]

Tags: EE research highlights MedE Lihong Wang

Laser-Induced Sound Waves Provide Live Panoramic Views of Tissue Functions

05-10-17

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering, and colleagues are now able to take a live look at the inner workings of a small animal with enough resolution to see active organs, flowing blood, circulating melanoma cells, and firing neural networks. "Photoacoustic tomography combines light and sound synergistically for high-resolution imaging of molecular contrast," says Professor Wang. [Caltech story] [Read the paper]

Tags: EE research highlights MedE Lihong Wang

Black Silicon Prevents Eye Implant from Gumming Up

04-13-17

Hyuck Choo, Assistant Professor of Electrical Engineering; Investigator, Heritage Medical Research Institute, and colleagues have developed an eye implant for glaucoma patients that could one day lead to more timely and effective treatment. Professor Choo has developed a passive system that eschews electronics and so needs no batteries and has no antennae. At just 600–800 micrometers in diameter, the sensor is the width of a few strands of hair. [Caltech story]

Tags: EE research highlights MedE Hyuck Choo

Seeing Deeper: An Interview with Lihong Wang

03-10-17

Using a combination of light and sound, Professor Lihong Wang is noninvasively peering deeper inside biological tissues than previously possible. His team uses three-dimensional photoacoustic microscopy and functional photoacoustic computed tomography to generate detailed color images of tumors and other structures inside the body. [Interview with Prof. Wang]

Tags: EE research highlights MedE Lihong Wang

The Future is Flat (For Lenses)

12-22-16

Andrei Faraon, Assistant Professor of Applied Physics and Materials Science, and colleagues have developed a system of flat optical lenses that can be easily mass-produced and integrated with image sensors, paving the way for cheaper and lighter cameras in everything from cell phones to medical devices. [Caltech story]

Tags: APhMS research highlights MedE Andrei Faraon

Building Better Batteries

12-19-16

Julia R. Greer, Professor of Materials Science and Mechanics, and colleagues have measured for the first time the strength of lithium metal at the nano- and microscale, a discovery with important implications for suppressing dendrite formation and improving lithium-ion batteries.  [Caltech story]

Tags: APhMS research highlights MedE MCE Julia Greer

Noise-Canceling Optics

10-10-16

Changhuei Yang, Professor of Electrical Engineering, Bioengineering, and Medical Engineering, and colleagues have created the visual analogue of noise-canceling headphones—a camera system that can obtain images of objects obscured by murky media, such as fog or clouds, by canceling out the glare. Their device selectively cancels the scattered light, leaving only the light that is reflected or bounced off the objects and has slipped back through the murk unmolested. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE

Your Future is Calling

10-03-16

Professor Morteza Gharib was one of the speakers at a recent symposium celebrating the Caltech–City of Hope Biomedical Research Initiative which provides seed grants to accelerate the development of basic scientific research and its translation into biomedical applications. Professor Gharib’s presentation was focused on measuring the ejection fraction, the fraction of blood that is ejected from the heart with each heartbeat. The group has designed a small piece of hardware that can connect to an iPhone and calculate a patient's ejection fraction—for less than $8. The device, called Vivio, gives comparable results to a cardiac magnetic resonance imaging, the gold standard in the medical industry for measuring heart health. [Caltech story]

Tags: research highlights GALCIT MedE Morteza Gharib

Tiny Diatoms Boast Enormous Strength

02-08-16

Researchers in the lab of Julia R. Greer, Professor of Materials Science and Mechanics, have recently found that diatom shells have the highest specific strength—the strength at which a structure breaks with respect to its density—of any known biological material, including bone, antlers, and teeth. [Caltech story]

Tags: APhMS research highlights MedE MCE Julia Greer